Table 1. A comparison of local regional recurrence rates between those underwent total thyroidectomy with prophylactic neck dissection (TT + CND) and those underwent total thyroidectomy (TT) alone.
| Author | Follow up period | No of patients |
Local regional recurrence rate (%) |
P-value | |||
|---|---|---|---|---|---|---|---|
| TT + CND | TT | TT + CND | TT | ||||
| So et al. 2012 (20) | 44.7 months (CND); 45.4 months (TT) | 119 | 113 | 1.7 | 3.5 | Not significant | |
| Lang et al. 2011 (21) | Median: 26 months | 82 | 103 | 3.7 | 2.9 | 1.0 | |
| Moo et al. 2012 (22) | 3.1 years | 45 | 36 | 4.4 | 16.7 | 0.13 | |
| Costa et al. 2009 (23) | Mean: 47 months (CND); 64 months (TT) | 126 | 118 | 6.3 | 7.7 | 0.83 | |
| Gemsenjager et al. 2003 (24) | Median: 6.5 years | 29 | 88 | 3 | 2 | Not reported | |
| Wada et al. 2003 (25) | Mean: 52 months | 235 | 155 | 0.43 | 0.65 | Not significant | |
| Syawak et al. 2006 (26) | Median: 24.5 months (CND); 70 months (TT) | 56 | 391 | 3.6 | 5.6 | Not reported | |
| Roh et al. 2007 (16) | Mean: 52 months | 82 (PCND: 40) | 73 | 0 | 2.6 | 0.37 | |
| Bardet et al. 2008 (27) | 15 months | 181 (with lateral neck dissection) | 161 | 2.8 | 3.7 | Not reported | |
Abbreviations: TT, total thyroidectomy; CND, central neck dissection.