Table 2. A comparison of the rate of hypoparathyroidism (hypocalcemia) between total thyroidectomy (TT) alone and total thyroidectomy with central neck dissection (TT + CND).
| Author | No of patients |
Transient hypocalcaemia/hypoparathyroidism (%) |
P-value | Permanent hypocalcaemia/hypoparathyroidism (%) |
P-value | ||||
|---|---|---|---|---|---|---|---|---|---|
| TT + CND | TT alone | TT + CND | TT alone | TT + CND | TT alone | ||||
| Moo et al. 2010 (22) | 45 | 35 | 31 | 5 | 0.001 | 0 | 5 | 0.41 | |
| So et al. 2012 (20) | 119 | 113 | 41.2 | 33.6 | 0.235 | 5.9 | 1.8 | 0.105 | |
| Lang et al. 2011 (21) | 82 | 103 | 18.3 | 8.7 | 0.017 | 2.4 | 1 | 1 | |
| Shindo et al. 2010 (45) | 122 | 134 | 13.1 | 25.4 | 0.02 | 0.8 | 0.7 | 0.99 | |
| Palestini et al. 2008 (46) | 93 | 148 | 26.9 | 12.8 | 0.003 | 0 | 2.7 | 0.2 | |
| Roh et al. 2007 (16) | 82 | 73 | 30.5 | 9.6 | 0.001 | 4.9 | 0 | 0.056 | |
| Sywak et al. 2006 (26) | 56 | 391 | 18 | 8 | 0.02 | 1.8 | 0.5 | 0.27 | |
| Giordano et al. 2012 (47) | 385 (unilateral), 308 (bilateral) | 394 | 36.1 (unilateral), 51.9 (bilateral) | 27.7 | 0.014 (unilateral), 0.001 (bilateral) | 7.0 (unilateral), 16.2 (bilateral) | 6.3 | 0.818 (unilateral), <0.001 (bilateral) | |
Abbreviations: TT, total thyroidectomy; CND, central neck dissection.