BB(t) | = | the time-dependent total body burden of the maternal animal (mg/kg); |
fam | = | the fraction of ingested chemical absorbed by the maternal animal (dimensionless); |
DImat(t) | = | the time-dependent dose administered to the maternal animal (mg/kg bw-day); and |
kelim | = | the first order elimination rate (days−1) = ln(2)/half-life (days). |