Table 2.
D-cycloserine | Alprazolam | Placebo | ||||
---|---|---|---|---|---|---|
CAPS | PSS | CAPS | PSS | CAPS | PSS | |
Baseline | 85.3 (79.3–91.9) | 32.9 (29.7–36.2) | 88.0 (82.3–93.6) | 32.4 (26.0–38.9) | 82.6 (75.8–89.4) | 32.4 (29.1–35.7) |
Post-tx | 65.9 (60.2–71.6) | 27.1 (24.3–29.9) | 69.6 (63.8–75.4) | 25.6 (22.5–28.7) | 63.8 (56.7–70.9) | 24.2 (20.2–28.1) |
3-month | 60.3 (54.4–66.2) | 25.2 (22.0–28.5) | 66.8 (59.6–74.0) | 26.1 (22.6–29.4) | 51.5 (43.6–59.5) | 21.4 (17.1–25.6) |
6-month | 56.00 (50.1–62.00) | 24.1 (20.5–27.6) | 63.4 (55.4–71.4) | 26.3 (22.5–30.1) | 46.9 (38.7–55.1) | 20.0 (15.9–24.0) |
12-month | 48.0 (41.0–55.0) | 22.6 (19.1–26.1) | 57.2 (50.6–63.8) | 24.2 (20.8–27.6) | 48.4 (41.0–55.8) | 21.7 (17.9–25.4) |
Note: DCS = D-cycloserine; CAPS = Clinician Administered PTSD Scale; PSS = PTSD Symptom Scale; post-tx = post-treatment assessment; All of these value are point estimates with a corresponding confidence interval (CI). The CI is needed to provide a range for the population parameter estimate. The CI around the baseline measure indicates that all of the groups started at the same point.