Table 5.

Prognostic factors in univariate and multivariate analysis

		p	Exp(B)	95% CI
Univariate analysis
ECOG Performance score	(0* vs. ≥1)	<0.0001
“B” symptoms	(No* vs. yes)	<0.0001
Bulky disease	(No* vs. yes)	0.0028
Stage	(I/ II* vs. III/IV)	0.0001
Extranodal involvement	(No* vs. yes)	<0.0001
Albumin	(≤3.2* vs. >3.2 g/dL)	<0.0001
ESR	(≤50* vs. >50 mm/h)	<0.0001
LDH	(≤460* vs. >460 U/L)	<0.0001
Haemoglobin	(≤12* vs. >12 gr/dL)	<0.0001
Radiotherapy	(No* vs. yes)	0.0113
Multivariate analysis
Albumin	>3.2 g/dL  (Ref.)	0.020	3.1	1.2–7.6
	≤3.2 g/dL)
LDH	≤460 U/L  (Ref.)	0.021	5.6	1.9–16.9
	>460 U/L
ECOG Performance score	0      (Ref.)	<0.001	17.5	5.7–54.1
	≥1
“B” symptoms	No      (Ref.)	0.003	2.8	1.4–5.4
	Yes

ESR: erythrocyte sedimentation rate; LDH: lactate dehydrogenase; Ref.: reference;

^*:Reference value for univariate analysis