Summary Statements |
1. Volume overload is often an overlooked factor in managing hypertension. Erythropoietin-induced hypertension and untreated sleep apnea are other important causes. |
2. Volume overload is associated with increased mortality in HD patients. |
3. The iterative trial-and-error method of dry weight assessment remains the current clinical standard in assessing volume status. |
4. Dietary salt restriction and individualizing dialysate sodium prescription may improve the feasibility of achieving dry weight. |
5. Probing dry weight can improve BP among hypertensive HD patients. The long-term risks and benefits of probing dry weight need to be examined in future trials. |
6. Delivery of dialysis of at least 4 hours duration three times a week may facilitate volume and hypertension control. |
7. Antihypertensive drugs are frequently needed to control hypertension but are an adjunct to facilitate volume control. Diuretics have little to no role in patients with ESRD. β-blockers may be preferred to other agents. |