Table 2.
Association of African-American race with hospitalized AKI
| HR for African-American Race (95% CI) | P Value | |
|---|---|---|
| Unadjusted | 1.27 (1.08 to 1.49) | 0.004 |
| Model 1: adjusted for demographics | 1.50 (1.27 to 1.77) | <0.001 |
| Model 2: model 1+CV risk factors and kidney function | 1.20 (1.01 to 1.43) | 0.04 |
| Model 3: model 2+APOL1 risk alleles | 1.28 (1.06 to 1.55) | 0.01 |
| Model 4: model 2+time-varying hospitalizations | 1.19 (1.00 to 1.42) | 0.04 |
| Model 5: model 4+insurance | 1.11 (0.91 to 1.34) | 0.30 |
| Model 6: model 5+income | 1.09 (0.89 to 1.32) | 0.40 |
Models include demographics (age and sex), cardiovascular (CV) risk factors (diabetes, hypertension, prevalent coronary heart disease, body mass index>30 kg/m2, uric acid, current smoking, and former smoking), kidney function (ACR [log 8-fold] and eGFR (knot at 60 ml/min per 1.73 m2), APOL1 risk alleles (two high-risk variants [yes or no]), time-varying hospitalizations (number of hospitalizations since baseline), insurance (yes or no), and income (<$12,000, $12,000–$24,999, $25,000–$49,999, and >$50,000).