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. Author manuscript; available in PMC: 2014 Jul 30.
Published in final edited form as: J Nucl Med. 2014 Mar 13;55(5):799–804. doi: 10.2967/jnumed.113.132118

FIGURE 4.

FIGURE 4

(A) IVIS luminescent images before administration of 89Zr-αGPC3. (B) Selected small-animal PET images of same animals showing tumor concordance in HepG2 tumor-bearing animals and lack of tumor uptake in RH7777, blocked, and heat-denatured controls. Signal saturation was permitted to enable comparisons between animals. Blue arrowheads indicate tumor location; red arrow indicates spleen. (C) Day 7 decay-corrected biodistribution of 89Zr-αGPC3 confirming low liver tumor uptake in RH7777, blocked, and heat-denatured controls.