Table 2.
Comparison of Activation Rate and Embryo Development Between Two Different Activation Protocols on Unfertilized Human Oocytes after IVF
| Activation treatment | A23187+6-DMAP | Strontium+6-DMAP | p value | Total % |
|---|---|---|---|---|
| Number of oocytes | 138 | 141 | 279 | |
| Oocytes activated % | 75.4 (104/138) | 46.8 (66/141) | 0.00 | 60.9 (170/279) |
| 1 PN (%) | 26.0 (27/104) | 13.6 (9/66) | 0.08 | 21.2 (36/170) |
| 2 PN (%) | 56.7 (59/104) | 54.5 (36/66) | 0.84 | 55.9 (95/170) |
| 3 PN (%) | 17.3 (18/104) | 31.8 (21/66) | 0.04 | 22.9 (39/170) |
| Number of cleavage % | 42.3 (44/104)) | 31.8 (21/66) | 0.20 | 38.2 (65/170) |
| 2–4 cells (%) | 18.2 (8/44) | 28.6 (6/21) | 0.35 | 8.2 (14/170) |
| 5–8 cells (%) | 38.6 (17/44) | 47.6 (10/21) | 0.59 | 15.9 (27/170) |
| >8 cells (%) | 34.1 (15/44) | 19.0 (4/21) | 0.26 | 11.2 (19/170) |
| Blastocysts % | 9.1 (4/44) | 4.8 (1/21) | 1.00 | 2.9 (5/170) |
IVF, in vitro fertilization; 6-DMAP, 6-diaminopurine; PN, pronucleus.