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. 2014 Jul 30;9(7):e102667. doi: 10.1371/journal.pone.0102667

Table 2. Gene Ontology categories in three different transcriptomes from samples of the Ixodes scapularis female synganglion: GO terms searching success, similarities and differences.

BioProcess Level 2 (GO term) % Sample Il-1 % Sample Il-2 % Sample 454
Metabolic and cellular processes 60.3 69.7 50.4
Biological regulation 8.9 11.6 9.2
Signaling 4.0 4.1 4.5
Response to stimulus 5.7 2.0 6.7
Developmental processes 1.9 1.3 3.7*
Immunity 0.4 0.3 0.8
Locomotion 0.5 0.2 0.8
Growth 0.4 0.1 0.7
Reproduction 0.5 0.1 0.9
Totals (% all categories) 82.5 89.5 73.2
Search success: total transcripts/(% all transcripts) 8,086 (19.6%) 8,445 (27.5%) 9,574 (46.4%)
BioProcess Level 2 (GO term) Metabolic and cellular processes 50.8 46.3 46.5
Biological regulation 5.3 5.9 7.3
Oxidation-reduction 4.1 3.3 3.1
Signaling 0.8 5.2* 1.3
Cellular response to stimulus 3.0 0.8* 3.3
Response to external stimuli 1.4 1.0 3.0
Cellular developmental processes 0.5 0.7 1.3*
Immunity 0.2 0.3 0.3
Hormonal metabolic processes 0.6 2.4* 0.1
Growth 0.0 0.1 0.2
Reproduction 0.5 0.3 0.9
Totals (% all categories) 67.2 66.3 67.3
Search success: total transcripts/(% all transcripts) 11,740 (28.5%) 23,573 (76.4%) 14,249 (69.1%)
Molecular Level 3 (GO term) Hydrolase activity 13.1 12.7 11.8
Transferase activity 12.6 11.9 9.5
Ion binding 11.7 10.8 8.3
Nucleotide binding 8.8 9.2 10.7
Nucleoside binding 0.1 6.8* 6.5
Nucleic acid binding 9.4 10.3 7.8
Tetrapyrrole binding 1.2 0.8 1.0
Protein binding 8.4* 10.0* 9.1
Carbohydrate binding 0.5 0.5 0.6
Carboxylic acid binding 0.3 0.2 0.2
Lipid binding 0.5 0.4 2.0
Oxireductases activity 6.5 4.8 8.0
Signal transducer activity 3.4 4.4 2.9
Neurotransmitter binding --- 0.1 0.1
Kinase regulatory activity --- 0.1 0.2
Transmembrane transporter activity 3.0 2.9 2.8
Nucleoside-triphosphatase activity 1.0 1.0 0.2
Enzyme inhibitor activity 0.7 0.5 0.8
Enzyme activator activity 0.6 0.5 0.2
Totals (selected gene categories) 81.8 65.5 83.3
Search success: total transcipts/(% all transcripts) 8,160 (19.8%) 17,660 (57.3%) 2,629 (12.74%)

* Major difference.