Table 4.
Proposed risk stratification and treatment strategies for prediabetes
| Risks and treatments | Low risk | Medium risk | High risk |
|---|---|---|---|
| Hemoglobin A1C % | 5.7–5.8 | 5.9–6.1 | 6.2–6.49 |
| Risk stratification | √ | √ | √ |
| Lifestyle modification, 16-week course | √ | √ | √ |
| Physical activity of at least 150 minutes per week | √ | √ | √ |
| Weight loss of 7% of body weight if BMI ≥ 25 kg/m2 | √ | √ | √ |
| Hemoglobin A1C < 5.7% | √ | √ | √ |
| Metformin therapy for patients with BMI ≥ 25 kg/m2 if no weight loss after 16-week lifestyle modification course | √ | ||
| Gastric bypass surgery for patients with BMI > 35 kg/m2 per guidelines for treating obesity and/or if no weight loss after lifestyle modification and/or metformin therapy | √ |
BMI = body mass index; √ = yes.