. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: Cancer. 2014 May 28;120(15):2264–2271. doi: 10.1002/cncr.28738

Table 4.

Multivariable analysis of factors associated with sexual interest and sexual dysfunction

	CARES Sexual interest^a		CARES Sexual dysfunction^a
	β (se)^b	p-value	β (se)^b	p-value
Treatment-associated amenorrhea
No amenorrhea/ No chemotherapy	Reference		Reference
Amenorrhea	0.37 (0.12)	0.003	0.20 (0.16)	0.21
No amenorrhea/Chemotherapy	0.30 (0.12)	0.02	0.20 (0.16)	0.23
Symptoms
Vaginal pain^c	0.11 (0.04)	0.002	0.62 (0.05)	<0.0001
Hot flashes	−0.02 (0.04)	0.52	−0.05 (0.05)	0.28
Weight problems	0.32 (0.05)	<0.0001	0.05 (0.06)	0.47
CARES body image	0.36 (0.04)	<0.0001	0.17 (0.05)	0.002
Fatigue	0.14 (0.09)	0.12	0.35 (0.11)	0.003
Musculoskeletal pain	0.07 (0.04)	0.10	0.04 (0.05)	0.43

Abbreviations: CARES, Cancer Rehabilitation Evaluation System; se, standard error

Adjusted for stage, age, race/ethnicity, treatment, partner status, time from diagnosis, and all variables included in table.

Positive coefficients with a p-value ≤0.05 are associated with higher CARES scores, which indicates significantly more sexual functioning concerns.

In non-sexually active women, “vaginal pain” includes the single item measuring vaginal dryness severity. In sexually-active women, “vaginal pain” includes items measuring both vaginal dryness and dyspareunia severity.