. Author manuscript; available in PMC: 2015 Jul 15.

Published in final edited form as: J Mol Biol. 2014 May 17;426(14):2617–2631. doi: 10.1016/j.jmb.2014.05.006

Table 4.

Comparison of F3284-8495 and some other RNHIs

Compound	PDB Code	Resolution Limit (Å)	IC₅₀, RT- RNase H (µM)	Number of Ligand His539 Contacts (< 4.0Å)
F3284-8495	4JE2	1.65	4.8	8
3QIN #1	3QIN	1.70	1.18	12
3QIP #2	3QIP	2.10	0.80	5
Manicol	3QLH	2.70	0.60	20
3QIO #3	3QIO	1.40	0.23	22
β-Thujaplicinol	3K2P	2.00	0.21	7
MK2	3LP1	2.20	0.12	8
MK1	3LP0	2.80	0.11	11