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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Biochem Pharmacol. 2014 Feb 19;89(1):141–147. doi: 10.1016/j.bcp.2014.02.006

Figure 2.

Figure 2

Figure 2A. H2O2 generation (closed symbols) and O2 uptake (open symbols) monitored with an Apollo 4000 Radical Ion Analyzer in Sf9 microsomes from baculovirus expressed hFMO1 (diamonds), hFMO2.1(triangles), hFMO3 (squares) with ETU substrate (50 μM), and hFMO2.1 without substrate (circles) at pH 7.4, 37°C. Substrate was added after a 5 minute pre-incubation with 1 mM NADPH.

Figure 2B. H2O2 yield as a percent of O2 consumption by human FMO1 (diamonds), FMO2.1 (triangles) and FMO3 (squares) over an incubation time of 60 minutes.