Table 2.
IBW algorithm | Height (inches)
|
Threshold height (inches) | % toxic at 400 mg/d | % with ABW < IBW | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | ||||
Wolfe2 | 100 | 105 | 110 | 115 | 120 | 125 | 130 | 135 | 140 | 145 | 150 | 155 | 160 | 165 | 170 | 175 | 180 | 67 | 80 | 10 |
Met Life women, small frame, mean15 | 109 | 112 | 115 | 118 | 121 | 124 | 127 | 130 | 133 | 136 | 139 | 142 | 145 | 148 | 151 | 154 | 157 | 69 | 94 | 10 |
Met Life women, large frame, mean15 | 130 | 133 | 136 | 139 | 143 | 148 | 150 | 153 | 157 | 160 | 163 | 166 | 169 | 172 | 175 | 178 | 181 | 62 | 16 | 31 |
NHLBI table10 | 123 | 127 | 131 | 135 | 140 | 144 | 148 | 153 | 158 | 162 | 167 | 172 | 177 | 182 | 186 | 192 | 197 | 63 | 29 | 27 |
Bergholz16 | 129 | 131 | 133 | 135 | 137 | 139 | 142 | 144 | 146 | 148 | 150 | 152 | 155 | 157 | 159 | 161 | 163 | 63 | 29 | 27 |
Michaelides8 | 98 | 101 | 105 | 108 | 112 | 116 | 119 | 123 | 127 | 131 | 135 | 138 | 142 | 146 | 150 | 154 | 158 | 70 | 98 | 5 |
Walvick7 | 114 | 118 | 121 | 125 | 128 | 132 | 135 | 139 | 142 | 146 | 149 | 153 | 156 | 160 | 163 | 167 | 170 | 66 | 70 | 16 |
Notes: Values given are ideal body weights in pounds corresponding to the algorithm of that row and the height of that column. Threshold height, the height at which 400 mg/d hydroxychloroquine exceeds 6.5 mg/kg/d for the ideal body weight algorithm represented on the row being examined. % toxic at 400 mg/d, the percentage of patients below the threshold height based on the sample of patients studied. % with ABW < IBW, the percentage of patients in whom the actual body weight falls below the ideal body weight based on the sample of patients studied.
Abbreviations: ABW, actual body weight; IBW, ideal body weight; Met Life, Metropolitan Life Insurance table for women; NHLBI, National Heart Lung and Blood Institute.