Table 3.
IBW algorithm | Height (cm)
|
Threshold height (cm) | % toxic at 400 mg/d | % with ABW < IBW | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
152 | 155 | 157 | 160 | 163 | 165 | 168 | 170 | 173 | 175 | 178 | 180 | 183 | 185 | 188 | 191 | 193 | ||||
Wolfe2 | 45.5 | 47.7 | 50.0 | 52.3 | 54.5 | 56.8 | 59.1 | 61.4 | 63.6 | 65.9 | 68.2 | 70.5 | 72.7 | 75.0 | 77.3 | 79.5 | 81.8 | 170 | 80 | 10 |
Met Life women, small frame, mean15 | 49.5 | 50.9 | 52.3 | 53.6 | 55.0 | 56.4 | 57.7 | 59.1 | 60.5 | 61.8 | 63.2 | 64.5 | 65.9 | 67.3 | 68.6 | 70.0 | 71.4 | 175 | 94 | 10 |
Met Life women, large frame, mean15 | 59.1 | 60.5 | 61.8 | 63.2 | 65.0 | 67.3 | 68.2 | 69.5 | 71.4 | 72.7 | 74.1 | 75.5 | 76.8 | 78.2 | 79.5 | 80.9 | 82.3 | 157 | 16 | 31 |
NHLBI table10 | 55.9 | 57.7 | 59.5 | 61.4 | 63.6 | 65.5 | 67.3 | 69.5 | 71.8 | 73.6 | 75.9 | 78.2 | 80.5 | 82.7 | 84.5 | 87.3 | 89.5 | 160 | 29 | 27 |
Bergholz16 | 58.6 | 59.5 | 60.5 | 61.4 | 62.3 | 63.2 | 64.5 | 65.5 | 66.4 | 67.3 | 68.2 | 69.1 | 70.5 | 71.4 | 72.3 | 73.2 | 74.1 | 160 | 29 | 27 |
Michaelides8 | 44.5 | 45.9 | 47.7 | 49.1 | 50.9 | 52.7 | 54.1 | 55.9 | 57.7 | 59.5 | 61.4 | 62.7 | 64.5 | 66.4 | 68.2 | 70.0 | 71.8 | 178 | 98 | 5 |
Walvick7 | 51.8 | 53.6 | 55.0 | 56.8 | 58.2 | 60.0 | 61.4 | 63.2 | 64.5 | 66.4 | 67.7 | 69.5 | 70.9 | 72.7 | 74.1 | 75.9 | 77.3 | 168 | 70 | 16 |
Notes: Values given are ideal body weights in kilograms corresponding to the algorithm of that row and the height of that column. Threshold height, the height at which 400 mg/d hydroxychloroquine exceeds 6.5 mg/kg/d for the ideal body weight algorithm represented on the row being examined. % toxic at 400 mg/d, the percentage of patients below the threshold height based on the sample of patients studied. % with ABW < IBW, the percentage of patients in whom the actual body weight falls below the ideal body weight based on the sample of patients studied.
Abbreviations: ABW, actual body weight; IBW, ideal body weight; Met Life, Metropolitan Life Insurance table for women; NHLBI, National Heart Lung and Blood Institute.