Fig. 3.

A: H. pylori infection of AGS cells upregulates miR-1289 expression. AGS cells were mock infected or infected with wild-type H. pylori (MOI = 100, for the indicated times) and the cellular content of miR-1289 was measured by RT-qPCR. Values are means ± SE (n = 3). B: patients infected with a cagA⁺ strain of H. pylori expression significantly higher levels of gastric mucosal miR-1289. RNA was isolated from human gastric biopsies from uninfected (UI) patients or cagA⁺ or cagA⁻ H. pylori-infected patients. MiR-1289 expression relative to an endogenously expressed small RNA, RNU44, was measured by RT-qPCR. Values are means ± SE (n = 3).