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Expression levels of representative genes upregulated in clusters 1 and 3. Lung mRNA was isolated and transcript expression levels of TIMP-1 (A), MMP-8 (B), and NFκB2 (C) were measured by real-time quantitative reverse transcription-polymerase chain reaction. Data are expressed as means ± SD (n = 6 mice in each time point). *P < 0.05; **P < 0.001.
