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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: ChemMedChem. 2014 Apr 1;9(8):1677–1682. doi: 10.1002/cmdc.201402051

Figure 1.

Figure 1

Structures of recently reported M5 PAMs (1-3), an M5-preferring orthosteric antagonist 4, the first highly selective M5 NAM 5 and a highly M1 selective orthosteric antagonist 6.