Induction of the human tissue factor (TF) promoter in endothelial cells. Shown are intracellular signaling pathways, transcription factors and DNA binding sites that regulate TF gene expression in response to different agonists. Receptor (R), oxidized phospholipids (oxPAPC), antiphospholipid antibody (APL-ab), aryl hydrocarbon receptor (AHR), thromboxane A2 (TXA2), thrombin (FIIa), indoxylsulfate (IS), vascular endothelial growth factor (VEGF), protease-activated receptor 1 (PAR-1).