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. 2014 Jun 16;28(8):1265–1275. doi: 10.1210/me.2014-1022

Figure 5.

Figure 5.

FKBP51 is a reciprocal regulator of GRα and PPARγ at metabolic genes. A, WT and 51KO MEFs were treated with or without 100 nM Dex for 2 hours followed by real-time PCR analysis of the indicated genes (±SEM; n = 6). B, WT and 51KO MEFs transfected with PPARγ2 were treated with or without rosiglitazone (Rosi) for 2 hours followed by real-time PCR of the indicated genes (±SEM; n = 6). All transcript expression was normalized to 18S mRNA. Statistical differences are indicated as follows: *, P > .05; **, P > .01; ***, P > .001; the same parameters apply for # and ∧ symbols. *, WT vs WT; #, 51KO vs 51KO; ∧, WT vs 51KO. PDK4, pyruvate dehydrogenase kinase; PEPCK, phosphoenolpyruvate carboxykinase; G6Pase, glucose-6- phosphatase.