Table 2.
MSKCC; Ex Vivo T Cell Depletion (n = 115), %(95%CI) |
M.D. Anderson; T Cell Replete (Tacrolimus/MTX) (n = 181), %(95%CI) |
HR (95% CI) | P Value | |
---|---|---|---|---|
Acute GVHD II-IV at day 100 | 5(2–11) | 18 (13–24) | 3.9 (1.5–9.9) | .005 |
Chronic GVHD at 3 years | 13 (8–22) | 53 (46–62) | 4.6(2.6–8.1) | <.001 |
NRM | ||||
Day 100 | 8 (4–15) | 3 (1–7) | 0.4(0.1–1.1) | .07 |
3 year | 24(17–34) | 16(11–23) | 0.6(0.3–1.1) | .10 |
PFS at 3 years | 18 (12–27) | 25 (19–33) | 1.3 (0.8–2.3) | .30 |
OS at 3 years | 57 (47–67) | 66 (58–74) | 0.7(0.5–1.1) | .20 |