Table 1.
Splice variant name | Affected domain | Number of amino acids added | Functional modification | References |
---|---|---|---|---|
mK44 | S0-S1 loop | 44 | decreased voltage and Ca2+ sensitivity, endoprotease cleavage | Korovkina et al., 2001, 2006; Curley et al., 2004 |
SV1 | S1 | 33 | endoplasmic reticulum retention | Zarei et al., 2001, 2004 |
STREX | S8-S9 loop | 59 | increased voltage and Ca2+ sensitivity, switches from PKA activation to inhibition | Saito et al., 1997; Benkusky et al., 2000; Tian et al., 2001; Zhu et al., 2005 |