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. 2014 Jul 31;5:289. doi: 10.3389/fphys.2014.00289

Table 1.

BKCa channel splice variants expressed in the myometrium.

Splice variant name Affected domain Number of amino acids added Functional modification References
mK44 S0-S1 loop 44 decreased voltage and Ca2+ sensitivity, endoprotease cleavage Korovkina et al., 2001, 2006; Curley et al., 2004
SV1 S1 33 endoplasmic reticulum retention Zarei et al., 2001, 2004
STREX S8-S9 loop 59 increased voltage and Ca2+ sensitivity, switches from PKA activation to inhibition Saito et al., 1997; Benkusky et al., 2000; Tian et al., 2001; Zhu et al., 2005