Table 2.

Expression and functions mediated by TLRs on γδ T cells.

TLR	Functions	References
TLR 2	Recognize LPS, enhance proliferation, induce IFNγ and CD107a expression, enhance IL17 secretion, expression transiently increases after burn injury, mitochondrial danger-associated molecular patterns (MTDs) induce expression and production of IL-1β, IL-6, IL-10, RANTES, and VEGF	(19, 116–120)
TLR3	Induce IFNγ production in conjunction with TCR stimulation, resistance to HSV induced encephalitis	(11, 121–123)
TLR4	Increases proliferation, IFN-γ release, and cytotoxic potential, activation following burn injury	(100, 125, 127, 130)
TLR7/9	Upregulate upon poly I:C costimulation, promote IL-17 production	(19, 124, 132)
TLR8	Reversal of immunosuppressive activity	(132, 134, 135)