Fig. 1:

Bacopa monniera selectively attenuates suppression of Superoxide Dismutase activity. 5% Tween 80 and B. monniera (120 mg/kg oral) did not alter SOD activity. Diazepam 1.75 mg/kg ip (fig 1A) and MK 801(0.17 mg/kg ip (fig 1D) significantly reduced SOD activity, while Scopolamine 0.1 mg/kg ip (C) and L-NNA 30 mg/kg ip (fig 1B) could not change it. B. monniera significantly attenuated diazepam induced suppression of SOD activity (fig 1A). On the other hand B. monniera did not produce significant impact of L-NNA (fig 1B) and MK 801 (fig 1D) pretreated mice, while it further suppressed SOD activity in Scopolamine pretreated mice (fig 1C). These values were obtained after normalization with total protein. Data was analyzed by ANOVA followed by LSD test. ‘s ’ indicates significant difference for treated group vs control group at p< 0.05, ‘b ’ indicates significant difference for treated group vs amnesic agent (diazepam/ scopolamine/L-NNA//MK 801) group at p < 0.05.