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. 2014 Jul 31;5:229. doi: 10.3389/fgene.2014.00229

Figure 1.

Figure 1

Functional mapping of protein kinase A (PKA) in intact adult S. mansoni. Male worms were fixed immediately after perfusion and stained with anti-phospho antibodies (green) to localize activated PKA. Image shows z-axis projection from intact worm in maximum pixel brightness mode. Intense staining reveals PKA activation particularly associated with the nervous system including in the ventral nerve cords (VNC), connecting cerebral commissures (CC), anterior ganglia (AG), complex nerve plexus (NP) associated with the oral sucker (OS) and nerve endings (NE) at the tegument surface. Bar = 100 μm. Adapted from De Saram et al. (2013).