Table 1.

Selected examples of orthologous protein kinases in S. mansoni and C. elegans with functional annotations shown for C. elegans.

Relative quantitative transcript expression (QTE) data for cercariae (Cerc), 3 and 24 h schistosomules (3 and 24 h S), and adult worms were extracted from GeneDB [www.Genedb.org (Protasio et al., 2012)]; representing 0–0.2, 0.2–0.4, 0.4–0.6, 0.6–0.8, and 0.8–1.0 relative expression, respectively. Smp protein identifiers were queried in PhylomeDB (www.phylomedb.org) to obtain orthologous identifiers for C. elegans proteins, and protein sequence compared using BLAST (http://blast.ncbi.nlm.nih.gov). Curated data on Uniprot (www.Uniprot.org) and Wormbase (www.wormbase.org) were used for phenotype annotation.