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. Author manuscript; available in PMC: 2014 Jul 31.
Published in final edited form as: Nat Biotechnol. 2013 Nov 3;31(12):1119–1125. doi: 10.1038/nbt.2727

Figure 2.

Figure 2

Clustering and ordering mammalian sequences with LACHESIS. (a) The results of LACHESIS clustering on the de novo human assembly. Shown on the x-axis are the 7,083 scaffolds (total length: 2.49 Gb) that are large (≥25 AAGCTT restriction sites) and not repetitive (Hi-C link density less than 2 times average), which LACHESIS uses as informative for clustering. The y-axis shows the 23 groups created by LACHESIS, with the order chosen for the purposes of clarity. The color scheme is the standard SKY (spectral karyotyping) color scheme for human. (b) The results of LACHESIS ordering and orienting of 579 scaffolds within the group from a corresponding to human chromosome 1. On the x-axis is the true position of these scaffolds along human chromosome 1. On the y-axis is the order in which LACHESIS has placed these scaffolds. Also listed in the panel are the chromosome name, the number of scaffolds in the derived ordering and the reference length of this chromosome. (c) The results of LACHESIS clustering on the de novo mouse assembly. Shown on the x-axis are the 8,594 scaffolds (total length: 1.94 Gb) that are large and not repetitive, which LACHESIS uses as informative for clustering. The y-axis shows the 20 groups created by LACHESIS, with the order chosen for the purposes of clarity. The color scheme is as in a. (d) The results of LACHESIS ordering and orienting of 781 scaffolds within the group from c corresponding to mouse chromosome 1. The plotting is as in b.