Table 3.
6 month change in endpoint | ANCOVA model | ||||
---|---|---|---|---|---|
Echocardiogram | N* | Vitamin D | Placebo | Vitamin D – Placebo |
p-value |
| |||||
Ejection fraction | 19, 15 | 0.8 ± 4.5 | 2.3 ± 3.5 | −0.8 | 0.56 |
LV septal wall thickness | 19, 15 | 0.0 ± 0.2 | 0.0 ± 0.1 | 0.0 | 0.49 |
LV posterior wall thickness | 19, 15 | 0.0 ± 0.2 | 0.0 ± 0.1 | 0.1 | 0.25 |
LV mass | 19, 15 | −11 ± 40 | −17 ± 47 | −2 | 0.89 |
LV mass index | 19, 15 | −5 ± 19 | −8 ± 21 | −1 | 0.92 |
e/e’ septal mitral annulus | 19, 14 | −1.0 ± 5.2 | −4.1 ± 8.0 | 1.1 | 0.61 |
Quantitative EF 4 chamber view |
17, 14 | −1.0 ± 13.8 | 10.4 ± 13.7 | −3.7 | 0.33 |
Quantitative EF 2 chamber view |
18, 14 | 1.1 ± 17.1 | 4.9 ± 11.4 | 0.9 | 0.84 |
| |||||
KCCQ | |||||
| |||||
Overall Summary Score | 25, 27 | 8.9 ± 20.4 | 2.2 ± 13.0 | 6.2 | 0.16 |
Clinical Summary Score | 25, 27 | 8.4 ± 17.0 | 0.3 ± 12.5 | 7.0 | 0.09 |
Physical limitations | 25, 27 | 7.1 ± 18.7 | 1.6 ± 14.1 | 5.1 | 0.25 |
Total symptoms | 25, 27 | 9.7 ± 22.8 | −1.0 ± 16.7 | 7.5 | 0.15 |
Quality of life | 25, 27 | 9.0 ± 28.1 | 4.6 ± 17.5 | 6.4 | 0.27 |
Social limitations | 24, 27 | 9.9 ± 33.0 | 3.7 ± 19.9 | 5.6 | 0.43 |
A subset of participants was evaluated by echocardiography.
EF- ejection fraction
LV – left ventricular
KCCQ –Kansas City Cardiomyopathy Questionnaire