Fig. 5.

CtpA is required for virulence in S. aureus. Two groups, each consisting of ten mice, were infected with the WT or ctpA⁻ mutant strain via tail vein injection. Mouse survival was monitored over a 7-day period (a), and analysed using a Kaplan–Meier survival curve. Statistical significance was determined using the log rank test (*P≤0.05). Following this, surviving mice were killed and the bacterial burden of internal organs was determined (b–e). Statistical significance was determined using a Mann–Whitney test (WT n = 4, ctpA⁻ mutant n = 9; *P≤0.05).