Table 1.
Baseline Characteristics of Included Participants of the Comprehensive Dialysis Study (CDS)a
| Characteristic | No. (%)
|
P Value | ||
|---|---|---|---|---|
| Cohort (n = 1576) | Frail (n = 1155) | Not Frail (n = 421) | ||
| Age, mean (SD), y | 59.6 (14.2) | 60.0 (14.0) | 58.3 (14.6) | .03 |
| Male sex | 874 (55.5) | 594 (51.4) | 280 (66.5) | <.001 |
| White race | 1084 (68.8) | 809 (70.0) | 275 (65.3) | .07 |
| Current smoker | 111 (7.0) | 89 (7.7) | 22 (5.2) | .09 |
| Medicaid vs other payer | 373 (23.7) | 307 (26.6) | 66 (15.7) | <.001 |
| eGFR, mean (SD), mL/min/1.73 m2 | 10.0 (4.45) | 10.4 (4.52) | 8.8 (4.04) | <.001 |
| Albumin, mean (SD), g/dLb | 3.18 (0.71) | 3.15 (0.70) | 3.26 (0.71) | .02 |
| Hemoglobin, mean (SD), g/dLc | 10.08 (1.77) | 10.14 (1.76) | 9.92 (1.77) | .04 |
| Hemodialysis | 1411 (89.3) | 1038 (89.9) | 373 (88.6) | .53 |
| Comorbidity | ||||
| Diabetes mellitus | 820 (52.0) | 650 (56.3) | 170 (40.4) | <.001 |
| Congestive heart failure | 474 (30.1) | 381 (33.0) | 93 (22.1) | <.001 |
| Atherosclerotic heart disease | 367 (23.3) | 288 (24.9) | 79 (18.8) | .01 |
| CVA/TIA | 112 (7.1) | 96 (8.3) | 16 (3.8) | .002 |
| Peripheral vascular disease | 226 (14.3) | 189 (16.4) | 37 (8.8) | <.001 |
| COPD | 120 (7.6) | 104 (9.0) | 16 (3.8) | <.001 |
| Cancer | 95 (6.0) | 71 (6.2) | 24 (5.7) | .74 |
Abbreviations: COPD, chronic obstructive pulmonary disease; CVA/TIA, cerebrovascular accident/transient ischemic attack; eGFR, estimated glomerular filtration rate.
SI conversion factors: To convert albumin to grams per liter, multiply by 10; to convert hemoglobin to grams per liter, multiply by 10.
a
Data are presented as number (percentage) except where noted.
b
n=1199.
c
n=1412.