Table 3.
Cancer outcome: low grade (< 7) | Model 1: adjusted
|
Model 2: unadjusted
|
||||
---|---|---|---|---|---|---|
RRR | 95 % CI | p | RRR | 95 % CI | p | |
Black racea | 1.29 | 0.92–1.80 | 0.14 | 1.35 | 0.98–1.87 | 0.06 |
Age (years) | 0.99 | 0.97–1.01 | 0.26 | |||
BMI (kg/m2), relative to < 25 kg/m2 | 0.02# | |||||
25–29.99 | 0.58 | 0.38–0.90 | ||||
30–34.99 | 0.63 | 0.40–1.01 | ||||
≥35 | 0.62 | 0.34–1.12 | ||||
Total number of cores taken | 0.92 | 0.86–0.99 | 0.02 | |||
Abnormal DRE | 1.45 | 0.97–2.16 | 0.07 | |||
PSA (ng/ml) | 1.37 | 1.04–1.80 | 0.02 |
Cancer outcome: high grade ( ≥ 7) | Model 1: adjusted
|
Model 2: unadjusted
|
||||
---|---|---|---|---|---|---|
RRR | 95 % CI | p | RRR | 95 % CI | p | |
Black racea | 1.84 | 1.28–2.66 | 0.001 | 1.82 | 1.32–2.50 | < 0.001 |
Age (years) | 1.01 | 0.99–1.04 | 0.30 | |||
BMI (kg/m2), relative to < 25 kg/m2 | ||||||
25–29.99 | 0.55 | 0.34–0.86 | 0.02# | |||
30–34.99 | 0.53 | 0.32–0.88 | ||||
≥35 | 0.77 | 0.42–1.41 | ||||
Total number of cores taken | 0.97 | 0.90–1.05 | 0.52 | |||
Abnormal DRE | 3.41 | 2.29–5.07 | < 0.001 | |||
PSA (ng/ml) | 2.91 | 2.21–3.83 | < 0.001 |
Statistical analysis: multinomial logistic regression for cancer grade on biopsy
Models adjusted for age, log-PSA, BMI, DRE, and total number of cores taken
RRR relative risk ratio for no cancer versus low grade versus high grade, CI confidence interval, p p value
Likelihood ratio test
Reference group was white race