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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: J Immunol. 2014 Apr 30;192(11):4967–4976. doi: 10.4049/jimmunol.1301670

Figure 6. Determinants of tapasin-independent assembly.

Figure 6

A) Sequence alignments of HLA-B*4405 with tapasindependent HLA-Bw4 molecules and of HLA-B*0801 with tapasin-independent HLA-Bw6 molecules. B and C) Based on the sequence alignments, residues expected to contribute to tapasin-dependent and tapasin-independent HLA-B assembly are highlighted on the structures of HLA-B*4405 (pdb 1SYV) and HLA-B*0801 (pdb 1AGD).