Skip to main content
. 2014 Jul 31;10(7):e1003764. doi: 10.1371/journal.pcbi.1003764

Figure 5. Stability of persistent activity depends on the background synaptic activity and the activation of the dADP current.

Figure 5

A. Indicative traces of persistent activity termination (black) and maintenance (grey) when a second stimulus (100 Hz for 100 ms) arrives 1 sec (arrow) after the inducing stimulus (dADP = 0 mV, iNMDA-to-iAMPA: 2.3). B. Probability of persistent activity termination as a function of the number of synapses delivered to the interneuron (50-100-200) under control condition (iNMDA-to-iAMPA: 2.3, dADP = 0 mV, squares) and in the presence of background synaptic input (iNMDA-to-iAMPA: 1.9, dADP = 0 mV, rhombus). dADP activation (absence of background activity: iNMDA-to-iAMPA: 1.9, dADP = 2 mV, presence of background activity: iNMDA-to-iAMPA: 1.5, dADP = 2 mV) is shown with circles. The different iNMDA-to-iAMPA conditions were used to ensure similar induction probabilities.