Figure 5. Phylogenetic relationships among the 5′UTR, VP1 and 3D^pol sequences of enteroviruses from human and non-human primates.

Only non species C enteroviruses were considered in these trees. The 5′UTR, VP1 and 3D^pol trees were based on the alignments of partial sequences (positions according to EV-A71 strain BrCr numbering: 193–430 for 5′UTR, 2615–2903 for VP1 and 6034–6377 for 3D^pol regions). Only non species C enteroviruses whose partial or complete VP1 sequences could be generated were considered in this comparative analysis. Prototypes strains originating from non-human primates (▴) or humans (Δ) are indicated. All other non-human primates strains from previous studies are distinguished by black circles (•) and those from this study are color-coded according to virus types. Non-human primates-derived viruses characterized in this study are further highlighted by yellow stars whereas green stars specify viruses previously identified in Cameroon either from humans or non-human primates.