TABLE 2.
Impact of Unsuccessful Cytogenetic Analysis on complete remission, 4-week mortality and 5-year overall survival rates
| UC | Favorable | Intermediate | Unfavorable | Very Unfavorable | |||||
|---|---|---|---|---|---|---|---|---|---|
| p- value |
p- value |
p- value |
p- value |
||||||
| Remission | |||||||||
| CR Rate (%) |
43 | 80 | <0.01 | 58 | 0.01 | 46 | 0.72 | 30 | 0.04 |
| OR (95% CI) |
5.02 (2.68,9.4) |
<0.01 | 1.60 (1.00,2.58) |
0.05 | 0.93 (0.55,1.57) |
0.79 | 0.57 (0.33,1.0) |
0.05 | |
| Early Death | |||||||||
| 4-week (%) |
12 | 3 | >0.3 | 8 | >0.3 | 12 | >0.3 | 21 | 0.07 |
| OR (95% CI) |
0.41 (0.12,1.44) |
0.17 | 0.80 (0.37,1.71) |
0.56 | 1.26 (0.54,2.95) |
0.59 | 2.20 (0.98,4.96) |
0.06 | |
| Survival | |||||||||
| 5-year (%) |
16 | 55 | <0.01 | 26 | <0.01 | 14 | 0.79 | 2 | <0.01 |
| HR (95% CI) |
0.38 (0.27, 0.54) |
<0.01 | 0.71 (0.55, 0.91) |
0.01 | 1.20 (0.91, 1.57) |
0.19 | 2.14 (1.62, 2.84) |
<0.01 | |
Abbreviations: UC- Unsuccessful cytogenetics, CR- complete remission; OR- Odds Ratio, CI- Confidence Interval, HR- Hazard Ratio.