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. 2014 Jul 31;9(7):e102895. doi: 10.1371/journal.pone.0102895

Table 2. Summary of cap structures that were cross-validated by 2D-TLC and mass spectroscopy.

5′end structure Name Known RNAs with thismodification in human Biological function ofthis RNA sRNA fraction with thismodification (nt)
2,2,7mGp N2,N2,7-trimethylguanosine monophosphate snoRNA rRNA modification 20 nt–200 nt
2,2mGp N2,N2 dimethylguanosine monophosphate tRNA, rRNA 20 nt–200 nt
2,7mGp N2,7-dimethylguanosine monphosphate ND 20 nt–50 nt
7mGp 7-methylguanosine monophosphate tRNA, rRNA, mRNA 20 nt–50 nt 100 nt
2mGp 2-methylguanosine monophosphate tRNA 20 nt–200 nt
1mGp 1-methylguanosine monophosphate tRNA, snRNA translation 20 nt–50 nt 100 nt
Cmp 2′-O-methylcytidine monophosphate tRNA, rRNA, snRNA, mRNA translation, transcription 20 nt–200 nt
Gp 5′-guanosine monophosphate All 20 nt–200 nt
Cp 5′-cytosine monophosphate All 20 nt–200 nt
Ap 5′-adenosine monophosphate All 20 nt–200 nt
Up 5′-uridine monophosphate All 20 nt–200 nt

*: Unique to this fraction.

**: First time to be reported in mammals.