Table 3. Efficacy of treatment based on the morphological development of sand flea lesions.
| Treatment applied | ||||
| NYDA | KMnO4 | p-valueb | ||
| Abnormal development/total lesions (%)a | ||||
| Day 3 | All lesionsc | 41/54 (76%) | 22/50 (44%) | <0.001 |
| - early stages (IIa)d | 19/28 (68%) | 12/33 (36%) | 0.021 | |
| - later stages (IIb–IIIa)d | 22/26 (85%) | 10/17 (59%) | 0.080 | |
| Day 5 | All lesionsc | 65/72 (90%) | 31/58 (53%) | <0.001 |
| - early stages (IIa)d | 40/43 (93%) | 20/37 (54%) | <0.001 | |
| - later stages (IIb–IIIa)d | 25/29 (86%) | 11/21 (52%) | 0.012 | |
| Day 7 | All lesionsc | 79/86 (92%) | 45/71 (63%) | <0.001 |
| - early stages (IIa)d | 45/49 (92%) | 27/45 (60%) | <0.001 | |
| - later stages (IIb–IIIa)d | 34/37 (92%) | 18/26 (69%) | 0.040 | |
a
see definition in materials and methods.
b
dimeticone versus KMnO4 treatment.
c
The total number of lesions examined varied at follow up examinations, because some participants could not be examined at the days foreseen, especially at the weekends (see flow diagram).
d
according to the Fortaleza classification.