Table 5. Presence of mouth dryness, oral mucositis and nausea at each time point and association between each toxicity and change in taste function.
T0: Pre-chemo(baseline) | T1: Earlycycle 3 | T2: Midcycle 3 | T3: Latecycle 3 | T4: Earlyfinal cycle | T5∶2 monthspost-chemo | |
Mouth dryness | ||||||
Grade 0 | 92.3 | 55.6 | 63.8 | 81.3 | 63.8 | 87.8 |
Grade 1 | 7.7 | 40.0 | 29.8 | 16.7 | 29.8 | 12.2 |
Grade 2 | 0.0 | 4.4 | 6.4 | 2.1 | 6.4 | 0.0 |
Correlation with change in taste function | −0.052 | −0.019 | −0.078 | 0.059 | 0.043 | |
p value | 0.70 | 0.88 | 0.55 | 0.65 | 0.76 | |
Oral mucositis | ||||||
Grade 0 | 96.2 | 88.9 | 85.1 | 87.5 | 83.0 | 93.9 |
Grade 1 | 3.8 | 6.7 | 10.6 | 10.4 | 10.6 | 6.1 |
Grade 2 | 4.4 | 2.1 | 2.1 | 4.3 | ||
Grade 3 | 2.1 | 2.1 | ||||
Correlation with change in taste function | −0.018 | 0.072 | −0.12 | −0.063 | −0.029 | |
p value | 0.89 | 0.59 | 0.35 | 0.63 | 0.83 | |
Nausea | ||||||
Grade 0 | 96.2 | 57.8 | 73.9 | 89.4 | 76.6 | 91.8 |
Grade 1 | 1.9 | 13.3 | 10.9 | 6.4 | 6.4 | 4.1 |
Grade 2 | 1.9 | 28.9 | 15.2 | 4.3 | 17.0 | 4.1 |
Correlation with change in taste function | 0.003 | −0.11 | −0.091 | −0.096 | −0.10 | |
p value | 0.98 | 0.40 | 0.49 | 0.46 | 0.46 |
Notes. Data on presence of mouth dryness, oral mucositis and nausea are percentages.