Table 2. Profiles of Patients with ATF4-Positive or ATF4-Negative ESCCs.

Clinicopathological Features	Tumor ATF4 Expression		P Value
	Negative(n = 51)	Positive(n = 117)
Age	64.3(9.8)	63.9(9.7)	0.828
Sex
Male	35	82	0.850
Female	16	35
Drinking
Yes	26	63	0.732
No	25	54
Tumor site
Upper	11	29	0.707
Middle	24	47
Lower	16	41
Tumor differentiation
Well	26	53	0.549
Moderate	16	47
Poor	9	17
TNM stage
I	21	17	0.001
II	19	56
III	11	44
Lymph node metastasis
Absent	43	52	0.000
Present	8	65