Table 2. Brain injury in newborns with HIE that develop infantile spasms.
Patient | Pattern | Cortical Extent | Midbrain | Pons | Medulla | Hypothalamus |
---|---|---|---|---|---|---|
1 | BG/T | + | + | - | - | - |
2 | Total | ++++ | ++ | ++ | - | + |
3 | Total | +++ | - | - | - | - |
4 | BG/T | + | + | - | - | - |
5 | Total | ++++ | + | ++ | + | - |
6 | BG/T | +++ | + | - | - | + |
7 | Total | ++++ | ++ | - | ++ | - |
8 | BG/T | + | - | + | - | - |
BG/T = basal ganglia/thalamus
Extent of cortical injury:
indicates 1-25%,
26-50%,
51-75%,
76-100% of cortex involved
Levels of brainstem: - indicates absence of injury, + mild, ++ moderate to severe
Hypothalamus: - indicates absence of injury, + presence