Table 2. Evaluation of I-TASSER models by using PROCHECK, ProSA-Web and VERIFY3D protein structure evaluation tools.
| α-DG | PROCHECK | ProSA | ||||
| Ramachandran plot statistics (%)a | VERIFY3D | |||||
| Core | Allowed | General | Disallowed | Compatibiliy score (%)b | z-score | |
| Wild-type zebrafish | 83.6 | 13.0 | 2.1 | 1.4 | 96.4 | −4.5 |
| V567D zebrafish | 84.2 | 12.3 | 3.4 | - | 92.1 | −4.6 |
| Wild-type murinec | 94.5 | 4.8 | - | - | 100.0 | −5.4 |
| I591D murine | 87.6 | 11.0 | 1.4 | - | 99.4 | −4.5 |
a
Ramachandran plot qualities show the percentage (%) of the residues belonging to the favoured (core), additionally allowed (allowed), generously allowed (general), disallowed region of the plot.
b
Percentage (%) of the residues with compatibility score above zero.
c
Data from De Rosa et al [17].