Table 1. Effect of BASF experimental compounds on phytoene accumulation in the presence of 200 µM norflurazon.
MEP target site | BASF | Inhibitionb | ||
#a | (%) | |||
DXS | ||||
1-Deoxyxylulose-5-phosphate synthase | ||||
3 | 11.1 | BC | ||
4 | 15.6 | BC | ||
5 | 27.2 | CD | ||
6 | 44.4 | DE | ||
DXR | ||||
1-Deoxyxylulose-5-phosphate reductoisomerase | ||||
7 | (117.7)c | A | ||
8 | 40.3 | DE | ||
IspD | ||||
2C–Methyl-d-erythritol 4-phosphate cytidyltransferase | ||||
9 | 20.6 | BCD | ||
10 | 26.0 | CD | ||
11 | 63.6 | E | ||
12 | 61.3 | E | ||
IspE | ||||
4-Diphosphocytidyl-2C-methyl-d-erythritol kinase | ||||
13 | 28.8 | CD |
Inhibition of phytoene accumulation by compound treatment was expressed in percentage of inhibition related to maximum accumulation in control assays. All compounds were tested at 100 µM.
Numbering corresponds to structures in Witschel et al. (2013) [41].
Means values followed by the same letter do not differ significantly at the 5% level by Duncan’s multiple range test.
Caused greater phytoene accumulation.