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. 2014 Aug;21(4):e630–e641. doi: 10.3747/co.21.1966

TABLE III.

Interval between drug discontinuation and skin testing (adapted from Brockow and Romano33)

Drug Interval
H1 antihistamines
  1st generation 1–3 Days
  2nd generation 7 Days
H2 antihistamines 2 Days
Imipramines and phenothiazines 5 Days
Beta-adrenergic blockers 48 Hours or according to their elimination half-life
Glucocorticoids (prednisolone equivalent)
  Long-term
    ≤10 mg None
    >10 mg 3 Weeks
  Short-term
    ≤50 mg 3 Days
    >50 mg 7 Days