Table 1. Basic hemodynamic parameters.
Prosthesis | Decellularized allograft | |||
Baseline | After replacement | Baseline | After replacement | |
HR (1/min) | 113±3 | 146±6* | 120±5 | 147±8* |
MAP (mmHg) | 71±4 | 41±2* | 77±4 | 47±2* |
CO (l/min) | 2.50±0.48 | 2.24±0.15 | 2.15±0.18 | 2.22±0.27 |
CI (ml/min/kgBW) | 79.9±15.4 | 71.5±5.1 | 77.3±7.2 | 78.5±8.2 |
SV (ml) | 22.1±3.9 | 15.3±0.7 | 18.1±1.7 | 15.5±2.5 |
Pes (mmHg) | 81±4 | 90±5 | 89±4 | 84±8 |
Ped (mmHg) | 7.7±0.3 | 7.7±0.8 | 6.5±0.5 | 6.8±1.5 |
τ (ms) | 33.2±2.5 | 28.3±4.2 | 30.6±1.1 | 29.5±5.3 |
TPR (mmHg/l/min) | 31.1±5.1 | 18.3±1.1 | 39.0±2.6 | 22.9±3.5* |
TPRI (mmHg/l/min/kgBW) | 0.99±0.16 | 0.59±0.04 | 1.40±0.09 | 0.84±0.16* |
SW (mmHg·ml) | 1641±320 | 1334±132 | 1521±203 | 1188±205 |
SWI (mmHg·ml/kgBW) | 52.5±10.4 | 42.7±4.6 | 55.1±8.3 | 42.3±7.3 |
PVA (mmHg·ml) | 2533±379 | 2484±412 | 3145±586 | 2222±347 |
Hemodynamic parameters in both groups at baseline and after total aortic arch replacement. Values of heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), cardiac index (CI), stroke volume (SV), left ventricular end-systolic (Pes) and end-diastolic pressure (Ped), time constant of left-ventricular pressure decay (τ), total peripheral resistance (TPR), total peripheral resistance index (TPRI), stroke work (SW), stroke work index (SWI) and pressure-volume area (PVA) are shown as mean±SEM. *:p<0.05 vs. baseline.