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. 2014 Jun 19;42(13):8500–8515. doi: 10.1093/nar/gku513

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© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — MPV17L2 gene silencing causes condensation of mtSSU proteins in foci that frequently coincide or overlap with enlarged mitochondrial nucleoids. HeLa cells treated with a random dsRNA (NT) or a specific siRNA for MPV17L2 (siR2) were analysed by confocal microscopy with antibodies to MRPS18B, MRPS27 and MRPS45 (red), the DNA was detected by anti-DNA (green) antibody. Co-localization of the ribosomal-specific red signal and DNA-specific green signal appears yellow in the merged images.