Figure 6. CXCR6 deficiency inhibits fibronectin and collagen I expression in the kidney.
A. Representative photomicrographs of fibronectin immunofluorescence staining of kidneys 2 weeks after UUO. Scale bar: 25 µm. B. Quantitative analysis of fibronectin positive area of kidneys 2 weeks after UUO. ** P <0.01 versus WT controls, + P <0.05 versus KO UUO, and # P <0.05 versus WT UUO. n=6 per group. C. Representative photomicrographs of collagen I immunofluorescence staining of kidneys 2 weeks after UUO. Scale bar: 25 µm. D. Quantitative analysis of collagen I positive area of kidneys 2 weeks after UUO. ** P <0.01 versus WT controls, + P <0.05 versus KO UUO, and # P <0.05 versus WT UUO. n=6 per group. E. Representative Western blots show the protein levels of fibronectin and collagen I of kidneys 2 weeks after UUO. F. Quantitative analysis of fibronectin and collagen I protein expression of kidneys 2 weeks after UUO. * P < 0.05 versus WT controls, + P < 0.05 versus s KO UUO, and # P < 0.05 versus WT UUO. n=6 per group.