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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Kidney Int. 2014 Mar 19;86(2):327–337. doi: 10.1038/ki.2014.64

Figure 7. CXCR6 deficiency in bone marrow-derived cells inhibits myeloid fibroblast accumulation and collagen deposition in the kidney.

Figure 7

A. Representative photomicrographs of kidney sections from WT or KO mice transplanted with CXCR6+/+ or CXCR6−/− bone marrow cells 1 week after UUO stained for CD45 (red), PDGFR-β (green), and DAPI (blue). Scale bar: 25 µm. B. Quantitative analysis of CD45+ and PDGFR-β+ fibroblasts in the kidneys. **p<0.01 versus WT → WT CON; #p<0.05 versus WT → WT UUO; +p<0.05 versus KO → WT UUO; ^p<0.05 versus KO→KO CON; $ p<0.05 versus KO→KO UUO; && p<0.01 versus WT→KO UUO. n=5–6 per group. C. Representative photomicrographs of kidney sections stained with Sirius red. Scale bar: 50 µm. D. Quantitative analysis of renal interstitial collagen content in different groups as indicated. **p<0.01 versus WT → WT CON; #p<0.05 versus WT → WT UUO; +p<0.05 versus KO → WT UUO; ^p<0.05 versus KO→KO CON; $ p<0.05 versus KO→KO UUO; && p<0.01 versus WT→KO UUO. n=5–6 per group.