Table 1.
Quantitative histomorphometry
| Histomorphometry | Absolute /normalized | Conventional allograft | Revascularized allograft | p value |
|---|---|---|---|---|
| Mineralizing bone surface to total bone surface ratio (%) | Graft values (%), | 9 ± 9 | 19 ± 5 | 0.01 |
| normalized values (%)*, | 30 ± 24 | 78 ± 26 | 0.002 | |
| p value graft versus contralateral | 0.008 | 0.039 | ||
| Mineral apposition rate (µm/day) |
Graft values (µm/day), | 1.3 ± 0.5 | 1.8 ± 0.4 | 0.07 |
| normalized values (%)*, | 105 ± 43 | 137 ± 39 | 0.16 | |
| p value graft versus contralateral | 0.38 | 0.05 | ||
| Bone formation rate to bone surface ratio (µm3/µm2/year) |
Graft values (µm3/µm2/year), | 44 ± 43 | 130 ± 47 | 0.006 |
| normalized values (%)*, | 35 ± 28 | 110 ± 53 | 0.005 | |
| p value graft versus contralateral | 0.008 | 0.95 |
Values are mean ± SD; *normalized values represent the percentage of graft values to contralateral (normal) values, therefore, a value higher than 100% indicates remodeling of a revascularized bone exceeds that of the contralateral normal femur.