Table 1.
Topical anti-inflammatory effect of the total extract and primary fractions obtained from Cryptostegia grandiflora leaves
| Treatment | Dose (mg/ear) | Ear weight differences (mg) | Inhibition percentage (%) |
|---|---|---|---|
| Control (TPA + acetone) | — — — | 13.5 ± 0.6 | — — — |
| Indomethacin | 0.5 | 7.4 ± 0.8 | 52.4 ± 6.2*** |
| Cryptostegia grandiflora | |||
| Total extract | 1.0 | 7.6 ± 0.1 | 42.1 ± 0.9*** |
| Ether fraction | 1.0 | 8.1 ± 0.8 | 41.8 ± 8.0*** |
| Dichloromethane fraction | 1.0 | 6.1 ± 0.5 | 52.9 ± 4.3*** |
| Methanol fraction | 1.0 | 12.2 ± 0.4 | 6.8 ± 3.2 |
Results are expressed as mean ± S.M.E. (n = 6) (***p <0.001 ANOVA, statistically significant compared with control group).